Inhibition of IκB kinase in Notch signaling activates FOXO3a
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منابع مشابه
Inhibition of IκB kinase in Notch signaling activates FOXO3a
The notch signaling pathway is highly conserved and plays an important role in the regulation of cellular proliferation, differentiation and apoptosis. Constitutive activation of notch signaling results in excessive cellular proliferation and a wide range of malignan-cies. However, notch can also act as a tumor suppressor, and its inactivation has been associated with an increased risk of spont...
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ژورنال
عنوان ژورنال: Cell Cycle
سال: 2012
ISSN: 1538-4101,1551-4005
DOI: 10.4161/cc.21067